Despite the strongest objections from every possible authority—including district attorney Harvey Dent—Dr. Harleen Quinzel's found herself with free access to every inmate in Arkham Asylum, where she desperately pursues a revolutionary and highly controversial cure to the insanity of Gotham. But her work with the city's super-criminals quickly muddies the waters of good and evil, and in the deepest, darkest padded rooms of Arkham, even the words of a mad clown start making sense!